Magnesium l-threonate, or magnesium l-threonate, is a synthesized form of magnesium that is created when a manufacturer combines magnesium with threonic acid. This acid is a product of the metabolic degradation of vitamin C. Magnesium l-threonate was first developed at MIT as a postdoctoral project by Dr. Inna Slutsky of TAU's Sackler School of Medicine.
It is the newest magnesium chelate and has been found to cross the blood-brain barrier effectively. Magnesium supplements are often chelated, meaning that magnesium molecules are attached to another molecule. This makes the supplement more bioavailable and stable. Research has shown that magnesium l-threonate may increase brain-derived neurotrophic factor (BDNF), a protein that stimulates the formation of new brain cells.
It also promotes brain development and reduces the likelihood of developing any brain-related disorder. Administration of chronic treatment with magnesium l-threonate has been found to increase activation of downstream signaling molecules in the hippocampus. It has also been used to treat anxiety disorders in rats by oral administration and investigating the basis of its treatment in memory of fear and extinction. When selecting a magnesium l-threonate supplement, there are several factors to consider.
Common adverse effects include watery stools, which usually occur when magnesium is taken in doses greater than 1000 mg. Life Extension NeuroMag is the best brand of magnesium l-threonate because it contains all the essential components and is available in capsule and powder form. Participants in research studies have received either a placebo or a dose of 1500 mg to 2000 mg of magnesium l-threonate over a 12-week period. Numerous research studies indicate that the beneficial components of magnesium l-threonate primarily target the brain.
Magnesium l-threonate has also been found to reduce anxiety in animals by decreasing the number of generalized fear-based memories. We have identified the top 5 brands that currently sell magnesium l-threonate at a reasonable price and use the highest quality standards for manufacturing and sourcing. Magnesium is essential for cell function and a lack of it can cause neurological disorders, so it's important to understand what you should look for and what you should avoid when buying magnesium l-threonate supplements.